Superheroes and You: A Practical Guide is, as the name suggests, a manual about superheroes. It was written by Doctor Two-Brains during the days when he was Professor Steven Boxleitner. Most of what WordGirl knew of how to be a superhero she learned from that book. Ironically, It even showed how to defeat a superhero or at least distract them. The book was mentioned and brought in the series a few times.
Alternate design used in "Showdown at the Super Secret Spaceship Hideout."